Inexact Newton matrix-free methods for solving complex biotechnological systems
Paweł Drąg, Marlena Kwiatkowska
Citation: Proceedings of the 2014 Federated Conference on Computer Science and Information Systems, M. Ganzha, L. Maciaszek, M. Paprzycki (eds). ACSIS, Vol. 2, pages 597–602 (2014)
Abstract. In the article a new approach for solving complex and highly nonlinear differential-algebraic equations (DAEs) was presented. An important kind of applications of DAE systems is modeling of biotechnological processes, which can have a very different course. An efficient solving of equations describing biotechnological industrial inlets results in better optimization of the processes and has a positive impact on the environment. Some of the mentioned processes were characterized by a highly nonlinear dynamics. To obtain the trajectories of the state numerically, the backward differentiation formula was used in the presented method. As a result, a large-scale system of nonlinear algebraic equations was obtained. To solve a such system, the inexact Newton matrix-free approach was proposed. The new algorithm was tested on a mathematical model of a fed-batch fermentor for penicillin production. The numerical simulations were executed in MATLAB using Wroclaw Center for Networking and Supercomputing.